International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2016, Volume : 4, Issue : 2
First page : (111) Last page : (117)
Article doi: http://dx.doi.org/10.18782/2320-7051.2166
Protective effect of ZnCl2 on toxicity produced by Microcystin-LR on Serum Calcium and Phosphate levels of freshwater catfish Heteropneustes fossilis
Chandra Prakash, Mani Ram Prasad, Abhishek Kumar, Diwakar Mishra, Archana Chaudhary and Sunil K. Srivastav*
Department of Zoology, D.D.U. Gorakhpur University, Gorakhpur 273009, India
*Corresponding Author E-mail: sunilsrivastav@hotmail.com
Received: 5.12.2015 | Revised: 16.01.2016 | Accepted: 20.01.2016
Abstract
The present study was aimed to investigate the protective effect of ZnCl2 on toxicity produced by microcystin-LR on freshwater teleost fish Heteropneustes fossilis. Fish were divided into Group A, B, C and D. Group A served as control. Fish from group B were injected microcystin-LR (2.5 µg/25 g) intraperitoneally at the initiation of the experiment and after 5, 10, 20 and 30 days. In group C, fish were treated similar to group B and kept in freshwater containing 5 mg ZnCl2/L. Fish from group D were kept in freshwater containing 5 mg ZnCl2/L. fish were sacrificed and blood samples were collected on 5, 10, 20, and 30 days and analyzed for serum calcium and inorganic phosphate levels. In group B decrease in serum calcium levels was recorded on day 10, 20 and 30. No significant change in the serum calcium levels was noticed in group C and D. In group B, serum phosphate levels decrease on day10, 20 and 30. No significant change in the serum phosphate levels was noticed in group C and D.
Keywords: Microcystin-LR, Serum Calcium, Serum Phosphate, Heteropneustes fossilis, ZnCl2.
Full Text : PDF; Journal doi : http://dx.doi.org/10.18782
Cite this article: Prakash, C., Prasad, M.R., Kumar, A., Mishra, D., Chaudhary, A. and Srivastav, S.K., Protective effect of ZnCl2 on toxicity produced by Microcystin-LR on Serum Calcium and Phosphate levels of freshwater catfish Heteropneustes fossilis, Int. J. Pure App. Biosci. 4(2): 111-117 (2016). doi: http://dx.doi.org/10.18782/2320-7051.2166
