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Biologically synthesized silver nanoparticles are being widely using in the field of medicine.
Extracellular biosynthesis of silver nanoparticles was carried out by using Strychnos potatorum
leaf extract for the reduction of silver ions in short period. The silver nanoparticles formation
was confirmed by the colour change of plant extracts. These silver nanoparticles were tested for
antibacterial activity by using disc diffusion method. The test cultures are Escherichia coli,
proteus vulgaris, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and
Klebsiella sp., were used. The antibacterial property of silver nanoparticles was analysed by
measuring the inhibition zone. The silver nanoparticles synthesized from leaf extracts of
Strychnospotatorum. Whereas the growth of Pseudomonas sp., and Proteus sp., were inhibited
maximum by the silver nanoparticles synthesized from leaf extract of Strychnospotatorum. The
results indicates that the silver nanoparticles may have an important advantage over conventional
antibiotics.
Key words: Strychnos potatorum, Silver nanoparticles synthesis, Pathogens, Antibacterial activity.