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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2017 , Volume 5, Issue 4
Page No. : 916-919
Article doi: : http://dx.doi.org/10.18782/2320-7051.5566

Applications of CRISPR-Cas system in Plant Pathology: A Review

Afsha Tabassum¹, Shweta² and Vishnutej Ellur^3*

^1&3Ph.D. student, Department of Plant Pathology, Washington State University, Pullman, Washington, USA ²Ph.D. student, Dept. of Genetics & Plant breeding, University of Agricultural Sciences, Raichur, Karnataka, India – 584104
*Corresponding Author E-mail: afshatabassum1@gmail.com
Received: 8.08.2017 | Revised: 16.08.2017 | Accepted: 17.08.2017

ABSTRACT

Gene editing of living organisms has been tired by scientists since the discovery of DNA. Earlier approaches of gene editing was using oligonucleotides, self-splicing introns etc. Zinc Finger Nucleases (ZFN’s) and TALENs are effective but not widely adapted. The CRISPR (Clustered Regularly Interspaced Palindromic Repeat) – Cas (CRISPR- associated) is hundreds of millions of years old found in bacteria as survival mechanism against infection of viruses. The mechanism of CRISPR-Cas was understood only in early 2000s. This review presents overview of CRISPR technology and its applications against Plant Pathogens including Fungi, Bacteria and Viruses.
Keywords: Gene editing, Zinc Finger Nucleases, TALENs, CRISPR-Cas, Plant Pathogens

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782/2320-7051.5566

Cite this article:

Tabassum, A., Shweta and Ellur, V., Applications of CRISPR-Cas system in Plant Pathology: A Review, Int. J. Pure App. Biosci. 5(4): 916-919 (2017). doi: http://dx.doi.org/10.18782/2320-7051.5566

No. 772, Basant Vihar, Kota

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