Archives

Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2020, Volume : 8, Issue : 2
First page : (448) Last page : (456)
Article doi: : http://dx.doi.org/10.18782/2582-2845.8042

Modulatory Effects of Carrot Juice in Cadmium Chloride Induced Genetic Damage in Swiss Albino Mice

K. Rudrama Devi*, Ravi Prasad, Rajitha and K. Pratap Reddy
Department of Zoology, Osmania University, Hyderabad
*Corresponding Author E-mail: rudramadevi_k@yahoo.com
Received: 12.03.2020  |  Revised: 17.04.2020   |  Accepted: 22.04.2020 

 ABSTRACT

In the present study, modulating effect of carrot juice against cadmium chloride induced clastogenicity in bone marrow cells of mice. When animals administered with various doses of carrot juice 20, 40, 80 ml/kg the results showed antimutagenic nature of plant extract. There was a significant increase in the percentage of chromosomal aberrations in 3.0mg/kg cadmium chloride treated animals. However when animals were co-administered seven days prior to the priming experiment the frequency of chromosomal arerrations were decresed in treated groups. and when stastically analysed the data was found to be significant.  Thus the results clearly indicate protective nature of carrot juice in cadmium chloride induced cytogenetic damage in somatic cells of mice.

Keywords: Cadmium chloride, Chromosomal aberrations, Carrot juice.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Rudrama Devi, K., Ravi Prasad, Rajitha, & Pratap Reddy, K. (2020). Modulatory Effects of Carrot Juice in Cadmium Chloride Induced Genetic Damage in Swiss Albino Mice, Ind. J. Pure App. Biosci. 8(2), 448-456. doi: http://dx.doi.org/10.18782/2582-2845.8042