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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2020, Volume : 8, Issue : 1
First page : (120) Last page : (126)
Article doi: : http://dx.doi.org/10.18782/2582-2845.7953

Evaluating Haemato-biochemical Status in Dogs Suffering from Gastroenteritis after Combined Antioxidant and Antibiotic Therapy

Deepika Kataria^1*, Divya Agnihotri¹, Tarun Kumar¹ and Jyoti Shunthwal^2
1Department of Veterinary Medicine, College of Veterinary Sciences, LUVAS, Hisar, 125004, Haryana, India
²Haryana Pashu Vigyan Kendra, Mahendergarh, LUVAS, Hisar, 125004, Haryana, India
*Corresponding Author E-mail: deepikakataria257@gmail.com
Received: 2.01.2020  |  Revised: 31.01.2020   |  Accepted: 6.02.2020 

 ABSTRACT

Eighteen dogs suffering from gastroenteritis were randomly enrolled into three groups, 6 dogs in each group. These groups were administered with different combinations of antibiotic (ampicillin-cloxacillin with metronidazole) and antioxidants (vitamin C and N-acetylcysteine) along with supportive therapy. Estimation of haemato-biochemical parameters along with serum electrolytes was done to evaluate comparative effect of antioxidants with antibiotic therapy. Haematological and biochemical parameters of affected dogs were compared with six healthy dogs on day 0, 3 and 5 of treatment trial. Increased levels of haemoglobin with increased packed cell volume, leucocytosis/leucopenia, neutrophilia with thrombocytopenia were observed in gastroenteritic dogs. Elevated liver and kidney function parameters along with decreased serum electrolytes were observed in all gastroenteritic dogs. The results of the study concluded that, group which was administered with both the antioxidants along with antibiotic showed better recovery than rest of the two groups although there was not much statistically significant difference observed in the parameters of different groups.

Keywords: Gastroenteritis, Ampicillin-cloxacillin with metronidazole, Antioxidants, Vitamin C and N-acetylcysteine

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Kataria, D., Agnihotri, D., Kumar, T., & Shunthwal, J. (2020). Evaluating Haemato-biochemical Status in Dogs Suffering from Gastroenteritis after Combined Antioxidant and Antibiotic Therapy, Ind. J. Pure App. Biosci. 8(1), 120-126. doi: http://dx.doi.org/10.18782/2582-2845.7953