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Indian Journal of Pure & Applied Biosciences (IJPAB)
Year : 2019, Volume : 7, Issue : 6
First page : (460) Last page : (464)
Article doi: : http://dx.doi.org/10.18782/2582-2845.7812

Evaluation of Anthelmintic Efficacy of Ethanolic Extract of Punica granatum in Goats

Avinash M. Gadhave¹, Vikas V. Karande^2*, B. C. Ghumare³, K. Kundu⁴,
S. N. Jadhav⁵ and P. P. Mhase⁶

¹M.V.Sc scholar, Department of Pharmacology and Toxicology,
^2,3Assistant Professor, Department of Pharmacology and Toxicology,
⁴Department of Parasitology,
⁵Assistant Professor, Department of Biochemistry,
⁶Assistant Professor, Department of Microbiology,
Krantisinh Nana Patil College of Veterinary Science, Shirwal Dist- Satara,
Bombay Veterinary College, Parel, Mumbai -400012, India
*Corresponding Author E-mail: drvikas111081@gmail.com
Received: 19.10.2019  |  Revised: 25.11.2019   |  Accepted: 3.12.2019  

 ABSTRACT

As per the 19¹ animal census of India, total population of goat is around 135.17 million contributing 26.40% of total animal population. Maharashtra shares about 6.24% of the total goat population. Helminthic infections are one of the constraints reducing the productivity of these small ruminants and manifested by symptoms like   anaemia, emaciation, enteritis, dehydration and death in kids. Chemotherapeutic agents mainly from benzimidazole group, imidathiazole and avermectins are used for the treatment of helminth infections. However, the cost effectiveness and increasing resistance to these chemotherapeutics is the largest field problem. Hence the present study was undertaken in order to evaluate the anthelmintic efficacy of Punica granatum in goats. Total 30 infected goats were divided into three groups comprising 10 animals in each. Pre-treatment EPG counts (Mean ±SE) of faecal samples from the groups A, B, and C were recorded as 665±177.81, 790±210.79 and 720±136.87 respectively. Group A consisted of ten helminthic infested goats (Mean EPG of 665). Group B animals (Mean EPG of 790) received treatment with fenbendazole @ 5 mg/kg b.wt orally. Group C animals (Mean EPG of 720) received treatment with ethanolic extract of P. granatum peel @ 200 mg/kg b.wt orally. Treatment group (B and C) showed significant (p≤0.01) increase in Hb, TEC, PCV and while the EPG of faeces and TLC were found to be decreased significantly (p≤0.01) at 15th day and 28th day in gastrointestinal nematodes infected goats

Keywords: P. granatum, Benzimidazole, Anthelmintic, Goats

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Gadhave, A.M., Karande, V.V., Ghumare, B.C., Kundu, K., Jadhav, S.N., & Mhase, P.P. (2019). Evaluation of Anthelmintic Efficacy of Ethanolic Extract of Punica granatum in Goats, Ind. J. Pure App. Biosci. 7(6), 460-464. doi: http://dx.doi.org/10.18782/2582-2845.7812