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International Journal of Pure & Applied Bioscience (IJPAB)
Year : 2018, Volume : 6, Issue : 3
First page : (388) Last page : (397)
Article doi: : http://dx.doi.org/10.18782/2320-6564

Antimicrobial Activity of Honey on Pathogens Isolated from Patients with Allergic Respiratory Diseases

Kishori Tarfe¹* and Sunita Deshpande²

¹Department of Biotechnology, Smt. Chandibai Himathmal Mansukhani College,
Ulhasnagar, Maharashtra, India
²Former Professor, Seth G. S. Medical College & KEM Hospital, Parel, Mumbai, Maharashtra, India
*Corresponding Author E-mail: kishorikambli@gmail.com
Received: 27.05.2018  |  Revised: 25.06.2018   |  Accepted: 29.06.2018  

 

 ABSTRACT

Conventional medical treatments for allergic respiratory diseases include corticosteroids sometimes combined with antibiotics. Prolonged treatment with corticosteroids & antibiotics may lead to suppression of immune response as well as emergence of drug resistant strains. Therefore there is always need for alternative treatment. Honey has been used in medicine since ancient time. Bothe these traditional natural products have a wide range of activity against variety of pathogens. 140 sputum samples collected from patients with allergic respiratory diseases such as Asthma & ABPA, were tested for presence of pathogens. Total 20 bacterial isolates (K. pneumoniae, Staphylococcus aureus & Pseudomonas aeruginosa) & 12 fungal isolates (Candida species, A. fumigatus) were obtained. These isolates were tested for their susceptibility towards two varieties of Honey, Karvi & Jambul by Agar cup & Agar dilution method. Jambhul Honey was found to be more effective as compared with Karvi Honey. Honey varieties tested were found to be most effective at concentration 50% against Staphylococcus aureus followed by Klebsiella pneumoniae, P. aeruginosa, Candida species & A. fumigatus. Although Honey has been given as home remedy, both have remarkable activity on pathogens isolated from allergic respiratory infections. Presence of pathogens in respiratory tract of patients with respiratory allergies increases severity of their symptoms; therefore along with other medications Honey should be included in their treatment. Both Jambhul & Karvi Honey are Indian Honeys with great antimicrobial potential.

Key words: Asthma, ABPA, Karvi Honey, Jambhul Honey.

Full Text : PDF; Journal doi : http://dx.doi.org/10.18782

Cite this article: Tarfe, K. and Deshpande, S., Antimicrobial Activity of Honey on Pathogens Isolated from Patients with Allergic Respiratory Diseases, Int. J. Pure App. Biosci.6(3): 388-397 (2018). doi: http://dx.doi.org/10.18782/2320-7051.6564